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Huanbiao Mo, PhD

Professor    Department Chair
Education

PhD, Nutritional Sciences, University of Wisconsin-Madison

MS, Plant Physiology, Shanghai Institute of Plant Physiology, Chinese Academy of Sciences

BS, Biochemistry, Fudan University

Biography

Selected Invited Lectures/Oral Presentations

Dietary isoprenoids and cancer prevention. Westlake Frontiers in Nutrition Research Training Program, Zhejiang University, HangZhou, China, 2013.

Synergistic suppression of the mevalonate pathway and its potential applications. Wenzhou Medical College, Wenzhou, China, 2013.

Tumor-suppressive activity of geranylgeraniol in vitro. University of North Texas Health Science Center, Fort Worth, TX, 2013

Tumor-suppressive activity of geranylgeraniol in vitro. 12th International Conference on Functional Food Ingredients and Nutraceuticals in Chronic Disease, Southern Methodist University, Dallas, TX. 2012.

Tocotrienol’s effect on the HMGR pathway. 2nd International Tocotrienol Symposium, in conjunction with 103rd American Oil Chemist Society annual meeting, Long Beach, CA. 2012.

The mevalonate pathway – what do gastric injury and cancers have in common? TWU Science Seminar, 2011.

The impact of tocotrienols on the mevalonate pathway in tumors. East China Normal University, Shanghai, China, 2011.

The impact of isoprenoids on the mevalonate pathway in tumors. Zhejiang Hisun Pharmaceutical Co. Ltd, Zhejiang Province, China. 2011.

The impact of tocotrienols on the mevalonate pathway in tumors. 7th Japanese Society for Tocotrienol Research Conference, Sendai, Japan, 2010.

Tocotrienol, mevalonate and cancer. Universiti Teknologi Mara, Shah Alam, Selangor, Malaysia. 2010.

Tocotrienol and bone research. Universiti Kebangsaan Malaysia, Kuala Lumpur, Malaysia. 2010.

Role of the mevalonate pathway in tocotrienol-mediated tumor suppression. 1st International Conference on Tocotrienols & Chronic Diseases. Las Vegas, NV. 2010.

Anti-tumor activity of tocotrienols. New York Medical College, Valhalla, NY. 2010.


Patents

Elson CE, Mo H. Acyclic monoterpenoid derivatives. US patent 6,303,654.

Elson CE, Jung M, Mo H. Acyclic isoprenoid ether derivatives as chemotherapeutics. US patent 6,566,397.

Mo H, Elson CE, Peffley DM, Hentosh PM. Composition and method for treating cancer. US patent 7,074,825.

Memberships

American Society for Nutrition
Co-Chair, China Interest Group
2013-present

Society for Experimental Biology and Medicine
Membership Committee
2013-present

American Society for Nutrition Awards Program
Senior Educator & Mentor Nominating Panel
2013

American Society for Nutrition Awards Program
Senior Investigator (Group I) Nominating Panel
2012

North America Chinese Society for Nutrition
Secretary General
2012-present

American Association for Cancer Research
Member
2011-present

Society for Experimental Biology and Medicine
Member
2011-present

American Society for Nutrition
Chair, Diet and Cancer Research Interest Section
2010-2011

American Society for Nutrition
Member
2001-present

Institute for Cancer Research
University of North Texas Health Science Center
Member
2001

Center for Nutrition, Health and Food Genomics
Institute of Food Science and Engineering
Texas A & M University – College Station
Member, Advisory Board
2001-2006

Editorial Boards

Journal of Nutritional Health & Food Science
2013-present

Gastroenterology & Hepatology
2011-present

Journal of Nutritional Disorder & Therapy
2011-present

World Journal of Gastrointestinal Pathophysiology
2011-present

World Journal of Gastroenterology
2009-present

ISRN Oncology
2010-2013

Special Issue on Use of Medicinal Plants and
Natural Products for Treatment of Osteoporosis and Its Complications
Evidence-Based Complementary and Alternative Medicine
Guest Editor
2012

 

Awards and Honors

TWU Faculty Development Leave Award
2013

Scholarship Award
College of Health Sciences, TWU
2011

Publications

Torabi S, Mo H. (in press) trans, trans-Farnesol as a mevalonate-derived inducer of murine 3T3-F442A preadipocyte differentiation.Experimental Biology and Medicine (Maywood).

Cao HH, Chu JH, Kwan HY, Su T, Yu H, Cheng BCY, Fu X, Guo H, Li T, Tse AKW, Chou GX, Mo H, Yu ZL. (in press) Inhibition of the STAT3 signaling pathway contributes to apigenin-mediated anti-metastatic effect in melanoma. Scientific Reports.

Xia W, Mo H. (2016) Potential of tocotrienols in the prevention and therapy of Alzheimer’s disease. Journal of Nutritional Biochemistry 31:1-9.

Samuel F, Reddy J, Kaimal R, Segovia V, Mo H, Hynds DL. (2014) Inhibiting geranylgeranylation increases neurite branching and differentially activates cofilin in cell bodies and growth cones. Molecular Neurobiology 50:49-59. PMID: 24515839. PMCID: PMC4128908.

Shen CL, Mo H, Smith BJ, Chen CH, Chen L, Chyu MC, Kwun IS. (in press) Green tea and other fruit polyphenols attenuate deterioration of bone microarchitecture, in Polyphenols in Chronic Diseases and Mechanisms of Action of Polyphenols. eds R.R. Watson, V.R. Preedy & S. Zibadi. Elsevier publisher, volume 1, chapter 52

Elfakhani M, Torabi S, Hussein D, Mills N, Verbeck G, Mo H. (2014) Mevalonate deprivation mediates the impact of lovastatin on the differentiation of murine 3T3-F442A preadipocytes. Experimental Biology and Medicine (Maywood). 238:293-301.

Wang S, Moustaid-Moussa N, Chen L, Mo H, Shastri A, Su S, Bapat P, Kwun IS, Shen CL. (2014) Novel insights of dietary polyphenols and obesity. Journal of Nutritional Biochemistry 25:1-18. PMID: 24314860.

Mo H, Elfakhani M, Shah A, Yeganehjoo H. (2013) Mevalonate-suppressive tocotrienols for cancer chemoprevention and adjuvant therapy, in Tocotrienols: vitamin E beyond tocopherols. 2nd ed., eds B. Tan, R.R. Watson & V.R. Preedy. CRC Press, Boca Raton, FL. Page 135-149.

Mo H. (2013) The “one-two punch” of isoprenoids to inflammation (editorial).Journal of Nutritional Disorders & Therapy. 3:e109.

Shen CL, Kwun IS, Wang S, Mo H, Chen L, Jenkins M, Brackee G, Chen CH, Chyu MC. (2013) Function and mechanisms of green tea catechins in regulating bone remodeling. Current Drug Targets 14:1619-1630. PMID: 24041336.

Soelaiman IN, Das S, Shuid AN, Mo H, Mohamed N. (2013) Use of medicinal plants and natural products for treatment of osteoporosis and its complications (editorial). Evidence-Based Complementary and Alternative Medicine PMID: 23476703. PMCID: PMC3582079.

Chin KY, Mo H, Soelaiman IN. (2013) A review of the possible mechanisms of action of tocotrienol – a potential antiosteoporotic agent. Current Drug Targets14:1533-1541. PMID: 23859472.

Goktas Z, Moustaid-Moussa N, Shen CL, Boylan M, Mo H, Wang S. (2013) Effects of bariatric surgery on adipokine-induced inflammation and insulin resistance. Frontiers in Endocrinology 4:69. PMID: 23772224.

Fernandes N, Yeganehjoo H, Katuru R, DeBose-Boyd RA, Morris LL, Michon R, Yu ZL, Mo H. (2013) Geranylgeraniol suppresses the viability of human DU145 prostate carcinoma cells and the level of HMG CoA reductase. Experimental Biology and Medicine (Maywood) 238:1265-1274. PMID 24006306.

Cruz PM, Mo H, McConathy W, Sabnis NA, Lacko AG. (2013) The role of cholesterol metabolism and cholesterol transport in carcinogenesis: a review of scientific findings relevant to future cancer therapeutics. Frontiers in Pharmacology of Anti-Cancer Drugs 4:119. PMID: 24093019. PMCID: PMC3782849.

Jones S, Fernandes N, Yeganehjoo H, Katuru R, Qu H, Yu ZL, Mo H. (2013) β-Ionone induces cell cycle arrest and apoptosis in human prostate tumor cells.Nutrition and Cancer 65:600-610. PMID: 23659452.

Mo H, Yeganehjoo H, Shah A, Mo WK, Soelaiman IN, Shen C. (2012) Mevalonate-suppressive dietary isoprenoids for bone health. Journal of Nutritional Biochemistry 23:1543-1551. PMID: 22981371.

Shen CL, von Bergen V, Chyu MC, Jenkins MR, Mo H, Chen CH, Kwun IS. (2012) Fruits and dietary phytochemicals in bone protection. Nutrition Research32:897-910. PMID: 23244535.

Zeng S, Wang L, Chen T, Wang Y, Mo H, Qu H. (2012) Direct analysis in real time mass spectrometry and multivariate data analysis: a novel approach to rapid identification of analytical markers for quality control of traditional Chinese medicine preparation. Analytica Chimica Acta 733:38-47. PMID: 22704374.